Pauline Kiss

Real-world data and cardiovascular medications: diving into sex differences

Samenvatting

This work explored the sex differences in guideline-recommended treatment for the prevention and management of cardiovascular disease. The findings highlight consistent sex differences in cardiovascular care, often to the disadvantage of women. When studying electronic health records in the Netherlands, women had lower treatment and control of LDL cholesterol, were prescribed lower intensities of statins, were less likely to reach LDL cholesterol targets or undergo treatment uptitration. Sex differences were also observed in the pharmacological management of hypertensive patients and suggest a need for identifying optimal dosing practice for each sex.